SCHEMBL30258649

SCHEMBL30258649

CC(C)(C)[Si](C)(C)OCCCCCC1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.36
ITGA2B P08514 6/20 0.36
AVPR2 P30518 1/20 0.35
AVPR1A P37288 1/20 0.35
GNAO1 P09471 2/20 0.35
HRH3 Q9Y5N1 1/20 0.35
DUT P33316 1/20 0.34
FAAH O00519 1/20 0.33
TLR7 Q9NYK1 4/20 0.33
TLR8 Q9NR97 3/20 0.33
GNAI3 P08754 1/20 0.31
GNAI1 P63096 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12381955 0.86 HRH3 (0.33) ITGB3ITGA2BAVPR2AVPR1AGNAO1
Hydrochloric Acid SCHEMBL14762100 0.85 GNAO1 (0.34) ITGB3ITGA2BAVPR2AVPR1AGNAO1
SCHEMBL1326684 0.83 DUT (0.33) DUT
SCHEMBL1409568 0.78 TDP1 (0.38) HRH3DUT
SCHEMBL14245094 0.76 DUT (0.42) DUT
SCHEMBL27241092 0.76 DUT (0.42) DUT
SCHEMBL9007756 0.76 DUT (0.42) DUT
Hydrochloric Acid SCHEMBL14761471 0.76 TDP1 (0.40) GNAO1HRH3GNAI3GNAI1
SCHEMBL335223 0.75 ALDH1A1 (0.47) DUT
SCHEMBL336309 0.75 ALDH1A1 (0.47) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023059792-A1 CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS C4 THRAPEUTICS, INC. (US) 2023-04-13 WO disclosed