Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604300 | 0.81 | TSHR (0.46) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL10797362 | 0.81 | TSHR (0.46) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL11689491 | 0.79 | TSHR (0.44) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL10352664 | 0.77 | PTPN1 (0.43) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL10949262 | 0.77 | TSHR (0.42) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL10891703 | 0.76 | CYP1A2 (0.43) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL114442 | 0.75 | ALDH1A1 (0.46) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL1194233 | 0.75 | ALDH1A1 (0.46) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL28383675 | 0.75 | ALDH1A1 (0.46) | TSHRCYP1A2ALDH1A1LMNAFBP1 | |
| SCHEMBL27625431 | 0.74 | TSHR (0.39) | TSHRCYP1A2ALDH1A1LMNAFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008221-B | A kind of synthetic method of adjacent nitro benzyl chloride | 四川福思达生物技术开发有限责任公司 | 2019-04-19 | — | — | CN | claimed |
| CN-106008348-B | A kind of method of synthesizing pyrazole kresoxim-methyl intermediate | 四川福思达生物技术开发有限责任公司 | 2019-03-05 | — | — | CN | claimed |
| CN-106008221-A | Synthetic method for o-nitrobenzyl chloride | 四川福思达生物技术开发有限责任公司 | 2016-10-12 | — | — | CN | claimed |
| CN-106008348-A | Method for synthesizing pyraclostrobin intermediate | 四川福思达生物技术开发有限责任公司 | 2016-10-12 | — | — | CN | claimed |
| CN-105859625-A | Synthetic method for preparing pyraclostrobin intermediate from o-nitrobenzyl chloride | 四川福思达生物技术开发有限责任公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104370747-A | Method for synthesizing 3-chloro-4-methylaniline | UNIV ZHEJIANG TECHNOLOGY | 2015-02-25 | — | — | CN | claimed |
| JP-2012500848-A | — | — | 2012-01-12 | — | — | JP | claimed |
| US-8044214-B2 | Process for preparing isoxazole compounds | ANGUS CHEMICAL COMPANY (US) | 2011-10-25 | — | — | US | claimed |
| EP-2318381-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | claimed |
| WO-2010025035-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-04 | — | — | WO | claimed |
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | ANGUS CHEMICAL COMPANY | 2010-02-25 | — | — | US | claimed |
| CN-117003644-A | Novel method for synthesizing 2-chloro-6-nitrotoluene | 帕潘纳(北京)科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-112266326-A | Preparation method of dichlorotoluene nitride intermediate | 杭州臻挚生物科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| US-20210005931-A1 | NONAQUEOUS ELECTROLYTE, ENERGY STORAGE DEVICE, AND METHOD FOR PRODUCING ENERGY STORAGE DEVICE | GS YUASA INTERNATIONAL LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| EP-3477758-B1 | NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT | GS YUASA INT LTD (JP) | 2020-12-16 | — | — | EP | disclosed |
| US-5026821-A | Polymers of citric acid and diamines, a process for their preparation and their uses, in particular as carriers of drugs | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4098831-A | NITROBENZOTRICHLORIDE OR BROMIDE PROCESS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4020111-A | Propynyloxy alkyl arene insecticides | HENNESSY DOUGLAS J | 1977-04-26 | — | — | US | disclosed |
| US-3954793-A | INSECTICIDES | HENNESSY DOUGLAS J | 1976-05-04 | — | — | US | disclosed |
| US-3760013-A | 1-(DICHLORONITROMETHYL)BENZENE | DOW CHEMICAL CO | 1973-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | CYP11B2, CYP11B1, CYP3A7 | TSHR 3112/4885CYP1A2 15/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.