SCHEMBL3026153

SCHEMBL3026153

C=C(C)C(=O)OCC(CC)(COC(=O)C(=C)C)N=C=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 4/20 0.39
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3022662 0.87 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL3027135 0.84 TSHR (0.45) THRBTSHRALDH1A1
SCHEMBL5712202 0.81 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL1851512 0.79 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL152350 0.79 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL17868577 0.77 THRB (0.45) THRBTSHRALDH1A1
SCHEMBL14482474 0.74 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL17936309 0.74 THRB (0.38) THRBTSHRALDH1A1
SCHEMBL17653508 0.73 THRB (0.46) THRBTSHRALDH1A1
SCHEMBL23636 0.72 THRB (0.48) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000657-B2 Fluorine-containing urethane (meth)acrylate, curable composition, and antireflective film DIC CORPORATION (JP) 2018-06-19 US disclosed
US-20160208131-A1 FLUORINE-CONTAINING URETHANE (METH)ACRYLATE, CURABLE COMPOSITION, AND ANTIREFLECTIVE FILM DIC CORPORATION (JP) 2016-07-21 US disclosed
US-20130296594-A1 PHOTOCURABLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-11-07 US disclosed
US-20120264963-A1 PHOTOCURABLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-18 US disclosed
US-8217195-B2 Photocurable compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-07-10 US disclosed
US-20100197876-A1 PHOTOCURABLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160208131-A1 FLUORINE-CONTAINING URETHANE (METH)ACRYLATE, CURABLE COMPOSITION, AND ANTIREFLECTIVE FILM TET1, MGMT, AFF1 THRB 1411/4885TSHR 1352/4885ALDH1A1 343/4885
US-20130296594-A1 PHOTOCURABLE COMPOUND ACR, UMPS, UGT1A1 THRB 3780/4885TSHR 4329/4885ALDH1A1 14/4885
US-20120264963-A1 PHOTOCURABLE COMPOUND ACR, UMPS, UGT1A1 THRB 3780/4885TSHR 4329/4885ALDH1A1 14/4885
US-10000657-B2 Fluorine-containing urethane (meth)acrylate, curable composition, and antireflective film TET1, MGMT, AFF1 THRB 1411/4885TSHR 1352/4885ALDH1A1 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.