SCHEMBL30263147

SCHEMBL30263147

BrCCCc1ccccc1N(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28765851 0.89 TDP1 (0.41) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL806152 0.84 ALDH1A1 (0.39) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL5809365 0.83 CYP3A4 (0.42) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL28041959 0.81 LIPG (0.49) KCNH2LIPG
SCHEMBL28309227 0.80 ALDH1A1 (0.37) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL27910854 0.80 LIPG (0.51) KCNH2LIPG
SCHEMBL7922788 0.80 LIPG (0.51) KCNH2LIPG
SCHEMBL28160478 0.80 LIPG (0.51) KCNH2LIPG
SCHEMBL24631166 0.79 TP53 (0.39) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL3145597 0.77 LTB4R2 (0.39) CYP3A4CYP2D6CYP2C9LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819426-A Plant cytoplasmic membrane near-infrared fluorescent probe based on high specificity and preparation method and application thereof 浙江师范大学 2023-03-21 CN claimed
CN-115819426-A Plant cytoplasmic membrane near-infrared fluorescent probe based on high specificity and preparation method and application thereof 浙江师范大学 2023-03-21 CN disclosed