Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.65 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.53 |
| ▸ | TUBB | P07437 | 4/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.53 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263697 | 0.81 | TUBB4A (0.50) | JAK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30263741 | 0.80 | JAK2 (0.64) | JAK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3304801 | 0.80 | JAK1 (0.75) | JAK1NUDT1EGLN2JAK2JAK3 | |
| SCHEMBL3090231 | 0.79 | JAK1 (1.00) | JAK1NUDT1EGLN2JAK2JAK3 | |
| SCHEMBL28985329 | 0.78 | JAK1 (0.45) | JAK1NUDT1BRD4TUBB4ATUBB | |
| SCHEMBL30263726 | 0.77 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14888861 | 0.76 | JAK1 (0.66) | JAK1NUDT1EGLN2KDM4ETSHR | |
| SCHEMBL3098319 | 0.76 | NUDT1 (0.63) | JAK1NUDT1EGLN2CA1CA2 | |
| SCHEMBL3215698 | 0.76 | NUDT1 (0.67) | JAK1NUDT1EGLN2JAK2JAK3 | |
| SCHEMBL3212521 | 0.76 | NUDT1 (0.67) | JAK1NUDT1EGLN2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819425-A | Triazolo hexa-nitrogen heterocyclic-2-amine compound and preparation method and application thereof | 五邑大学 | 2023-03-21 | — | — | CN | disclosed |