Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502281 | 0.94 | CA1 (0.38) | CA1CA2CA9LCKPKM | |
| SCHEMBL11977445 | 0.88 | CA1 (0.46) | CA1CA2CA9LCKPKM | |
| SCHEMBL3035762 | 0.79 | LCK (0.44) | LCKPKMS1PR3S1PR4MAPT | |
| SCHEMBL289980 | 0.76 | LCK (0.39) | LCKPKMS1PR3KMT2AKDM4E | |
| SCHEMBL3011716 | 0.76 | LCK (0.41) | LCKPKMS1PR3KDRS1PR4 | |
| SCHEMBL3032468 | 0.74 | LCK (0.39) | LCKPKMS1PR3KMT2AKDM4E | |
| SCHEMBL16014723 | 0.73 | ESR2 (0.41) | CA1CA2CA9KDM4EALDH1A1 | |
| SCHEMBL3701195 | 0.73 | LCK (0.39) | LCKPKMS1PR3KDRS1PR4 | |
| SCHEMBL3652724 | 0.72 | ITGB3 (0.41) | LCKPKMS1PR3KMT2AALDH1A1 | |
| SCHEMBL30526738 | 0.71 | HPGD (0.42) | CA1CA2CA9LCKPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| EP-2212304-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| EP-2212304-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| WO-2009049844-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | CA1 680/4885CA2 243/4885CA9 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.