Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976313 | 0.84 | MAPT (0.48) | LCKMAPTPKMTAS1R3TAS1R1 | |
| SCHEMBL3011716 | 0.83 | LCK (0.41) | LCKMAPTPKMS1PR3S1PR4 | |
| SCHEMBL289980 | 0.81 | LCK (0.39) | LCKMAPTPKMS1PR3S1PR1 | |
| SCHEMBL3032468 | 0.81 | LCK (0.39) | LCKMAPTPKMS1PR3S1PR1 | |
| SCHEMBL3224938 | 0.81 | HDAC1 (0.36) | LCKMAPTPKMS1PR3S1PR1 | |
| SCHEMBL3035849 | 0.81 | MAPT (0.47) | MAPT | |
| SCHEMBL3701195 | 0.80 | LCK (0.39) | LCKMAPTPKMS1PR3S1PR4 | |
| SCHEMBL3026397 | 0.79 | CA1 (0.40) | LCKMAPTPKMS1PR3S1PR4 | |
| SCHEMBL3652724 | 0.79 | ITGB3 (0.41) | LCKMAPTPKMS1PR3S1PR4 | |
| SCHEMBL3210164 | 0.79 | HDAC1 (0.34) | LCKMAPTS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| US-8236828-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-07 | — | — | US | disclosed |
| EP-2212304-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| EP-2212304-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| EP-2212304-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009049844-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049844-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216850-A1 | INSECTICIDAL COMPOUNDS | CHRM1, ACHE, CHRM2 | LCK 2816/4885MAPT 2752/4885PKM 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.