SCHEMBL30264359

SCHEMBL30264359

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)CN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.46
▸ REN P00797 1/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ FOLH1 Q04609 2/20 0.44
▸ NTSR1 P30989 5/20 0.44
▸ NTSR2 O95665 3/20 0.44
▸ CAPN1 P07384 2/20 0.43
▸ NMUR2 Q9GZQ4 1/20 0.43
▸ CTSB P07858 1/20 0.43
▸ F2 P00734 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660884 0.88 CAPN1 (0.47) ACERENKMT2ANTSR1NTSR2
SCHEMBL30099425 0.87 KEAP1 (0.51) CAPN1NMUR2F2
SCHEMBL29470192 0.85 ACE (0.50) ACERENKMT2AFOLH1NTSR1
SCHEMBL30434738 0.85 NTSR2 (0.46) ACERENKMT2ANTSR1NTSR2
SCHEMBL29679979 0.85 CAPN1 (0.48) KMT2ANTSR1NTSR2CAPN1NMUR2
SCHEMBL30099668 0.84 ACE (0.55) ACERENKMT2ANMUR2F2
SCHEMBL31239042 0.84 NTSR1 (0.58) NTSR1NTSR2NMUR2
SCHEMBL29498697 0.83 ACE (0.50) ACERENKMT2AFOLH1NTSR1
SCHEMBL30974529 0.83 NMUR2 (0.52) NMUR2
SCHEMBL30800547 0.83 ACE (0.60) ACERENF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321218-A1 SARS-COV2 CORONAVIRUS RECONSTITUTED RBM AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-10-12 — — US disclosed
US-11746127-B2 Coronaviruses epitope-based vaccines RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-05 — — US disclosed
EP-4132949-A1 SARS-COV2 CORONAVIRUS RECONSTITUTED RBM AND USES THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2023-02-15 — — EP disclosed
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