Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658249 | 0.90 | ACE (0.57) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL30629285 | 0.90 | KEAP1 (0.50) | ACERENNMUR2 | |
| SCHEMBL30051880 | 0.89 | REN (0.53) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL30800547 | 0.87 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL30434874 | 0.87 | ACE (0.54) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL30436428 | 0.85 | ACE (0.59) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL30918793 | 0.84 | NAA50 (0.43) | ACERENNMUR2OPRK1STAT3 | |
| SCHEMBL30264359 | 0.84 | ACE (0.46) | ACERENKMT2AF2NMUR2 | |
| SCHEMBL30434949 | 0.84 | ACE (0.55) | ACERENMEN1KMT2AKDM4E | |
| SCHEMBL30434139 | 0.83 | ACE (0.54) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |