SCHEMBL30264643

SCHEMBL30264643

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](N)CS)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 12/20 0.54
▸ KISS1R Q969F8 2/20 0.52
▸ MC4R P32245 2/20 0.52
▸ NPBWR1 P48145 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264769 0.98 IL23R (0.53) IL23RKISS1RMC4RNPBWR1
SCHEMBL30264868 0.94 IL23R (0.56) IL23RMC4RNPBWR1
SCHEMBL29511016 0.94 OPRM1 (0.56) IL23RMC4RNPBWR1
SCHEMBL30264772 0.93 C5AR1 (0.51) IL23RKISS1RMC4R
SCHEMBL30264918 0.93 IL23R (0.54) IL23RKISS1RMC4R
SCHEMBL29480592 0.92 OPRD1 (0.57) IL23RKISS1RMC4RNPBWR1
SCHEMBL31184496 0.90 KISS1R (0.53) KISS1RMC4R
SCHEMBL29476415 0.90 KISS1R (0.53) KISS1RMC4R
SCHEMBL29476104 0.90 KISS1R (0.53) KISS1RMC4R
SCHEMBL29511055 0.90 KISS1R (0.53) KISS1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R IL23R 359/4885KISS1R 72/4885MC4R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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