SCHEMBL30264755

SCHEMBL30264755

C[C@@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 3/20 0.61
▸ KISS1R Q969F8 5/20 0.56
▸ ACE P12821 1/20 0.54
▸ MC4R P32245 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264864 0.98 GHSR (0.58) GHSRKISS1RACEMC4R
SCHEMBL31614972 0.94 KISS1R (0.54) GHSRKISS1RACEMC4R
SCHEMBL29476431 0.93 GHSR (0.53) GHSRKISS1RMC4R
SCHEMBL30264726 0.93 GHSR (0.53) GHSRKISS1RMC4R
SCHEMBL29476104 0.92 KISS1R (0.53) KISS1RACEMC4R
SCHEMBL29476415 0.92 KISS1R (0.53) KISS1RACEMC4R
SCHEMBL29511055 0.92 KISS1R (0.53) KISS1RACEMC4R
SCHEMBL31184496 0.92 KISS1R (0.53) KISS1RACEMC4R
SCHEMBL30786983 0.92 KISS1R (0.53) KISS1RACEMC4R
SCHEMBL29476441 0.92 KISS1R (0.55) GHSRKISS1RACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R GHSR 24/4885KISS1R 72/4885ACE 3813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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