SCHEMBL30265171

SCHEMBL30265171

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 11/20 0.61
▸ NPBWR1 P48145 9/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30401893 0.95 NPBWR1 (0.63) KISS1RNPBWR1
SCHEMBL31247913 0.92 NPBWR1 (0.57) KISS1RNPBWR1
SCHEMBL29825066 0.91 NPY4R (0.61) KISS1RNPBWR1
SCHEMBL29794137 0.91 GHSR (0.57) KISS1RNPBWR1
SCHEMBL30402141 0.90 NPBWR1 (0.58) KISS1RNPBWR1
SCHEMBL29483770 0.89 GHSR (0.60) NPBWR1
SCHEMBL29483769 0.89 GHSR (0.60) NPBWR1
SCHEMBL29641173 0.89 GHSR (0.60) NPBWR1
SCHEMBL2183733 0.88 NPBWR1 (0.54) KISS1RNPBWR1
SCHEMBL31018702 0.88 IL23R (0.58) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI (FR) 2024-07-04 — — US disclosed
EP-4392440-A2 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS River 2 Renal Corp. (US) 2024-07-03 — — EP disclosed
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SANOFI (FR) 2023-08-15 — — US disclosed
WO-2023028008-A2 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS RIVER 2 RENAL CORP. (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE RXFP1, RXFP2, RXFP4 KISS1R 1311/4885NPBWR1 56/4885
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SCTR, RXFP1, RXFP3 KISS1R 301/4885NPBWR1 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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