Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.52 |
| ▸ | CALCR | P30988 | 4/20 | 0.52 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974276 | 0.89 | F2 (0.61) | F2OPRM1OPRD1CALCRAPLNR | |
| SCHEMBL30455333 | 0.86 | F2 (0.52) | F2OPRM1OPRD1CALCRAPLNR | |
| SCHEMBL29794087 | 0.85 | F2 (0.58) | F2OPRM1OPRD1CALCRAPLNR | |
| SCHEMBL31683309 | 0.85 | CALCR (0.65) | F2KEAP1CALCRCRHR1CRHR2 | |
| SCHEMBL31437675 | 0.84 | REN (0.53) | F2CALCR | |
| SCHEMBL30480492 | 0.84 | OPRM1 (0.55) | OPRM1OPRD1 | |
| SCHEMBL30480493 | 0.84 | OPRM1 (0.55) | OPRM1OPRD1 | |
| SCHEMBL6516908 | 0.84 | REN (0.58) | OPRM1OPRD1 | |
| SCHEMBL29525618 | 0.84 | REN (0.58) | OPRM1OPRD1 | |
| SCHEMBL16684358 | 0.84 | F2 (0.65) | F2KEAP1OPRM1OPRD1CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776557-B | Polypeptide and application thereof, and DPP-IV inhibitor or hypoglycemic drug or health product | 中国科学院大连化学物理研究所 | 2023-02-28 | — | — | CN | claimed |
| CN-110776557-B | Polypeptide and application thereof, and DPP-IV inhibitor or hypoglycemic drug or health product | 中国科学院大连化学物理研究所 | 2023-02-28 | — | — | CN | disclosed |
| CN-110776557-B | Polypeptide and application thereof, and DPP-IV inhibitor or hypoglycemic drug or health product | 中国科学院大连化学物理研究所 | 2023-02-28 | — | — | CN | disclosed |