SCHEMBL30455333

SCHEMBL30455333

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.52
▸ APLNR P35414 2/20 0.52
▸ CALCR P30988 4/20 0.51
▸ OPRM1 P35372 3/20 0.50
▸ OPRD1 P41143 3/20 0.50
▸ C5AR1 P21730 1/20 0.48
▸ NMUR2 Q9GZQ4 1/20 0.46
▸ NMUR1 Q9HB89 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30454361 0.89 REN (0.51) F2APLNROPRM1OPRD1
SCHEMBL30233449 0.86 CALCR (0.58) F2APLNRCALCROPRM1OPRD1
SCHEMBL30266728 0.86 F2 (0.60) F2APLNRCALCROPRM1OPRD1
SCHEMBL30512510 0.86 CALCR (0.51) F2APLNRCALCRNMUR2NMUR1
SCHEMBL29842938 0.85 CALCR (0.58) F2APLNRCALCROPRM1OPRD1
SCHEMBL30233337 0.84 CALCR (0.60) F2APLNRCALCROPRM1OPRD1
SCHEMBL38662213 0.84 CALCR (0.60) F2APLNRCALCRC5AR1
SCHEMBL30974276 0.83 F2 (0.61) F2APLNRCALCROPRM1OPRD1
SCHEMBL29856457 0.83 CALCR (0.57) F2APLNRCALCRC5AR1
SCHEMBL30455799 0.83 APLNR (0.47) F2APLNRCALCRC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO claimed
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (OR) 2024-10-17 — — US disclosed
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA ARGLU1, TPX2, RXFP1 F2 2604/4885APLNR 122/4885CALCR 706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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