Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146099 | 0.90 | HRH3 (0.39) | HRH3MGLLHTTTSHRLIPG | |
| SCHEMBL27146833 | 0.89 | MGLL (0.38) | HRH3MGLLHTTTSHRLIPG | |
| SCHEMBL27137616 | 0.85 | CRBN (0.39) | MGLLHTTDDB1CRBN | |
| SCHEMBL27143092 | 0.84 | MGLL (0.42) | MGLLTSHRLIPG | |
| SCHEMBL29201746 | 0.83 | MGLL (0.39) | MGLLTSHR | |
| SCHEMBL31677239 | 0.83 | DRD2 (0.45) | — | |
| SCHEMBL30931910 | 0.83 | HRH3 (0.44) | HRH3HTTSPIN1 | |
| SCHEMBL27124624 | 0.83 | MGLL (0.41) | MGLLTSHR | |
| SCHEMBL30966215 | 0.83 | MGLL (0.38) | MGLLTSHR | |
| SCHEMBL31697885 | 0.83 | MGLL (0.39) | MGLLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |