Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143092 | 0.94 | MGLL (0.42) | MGLLTSHRHSD11B1CCR3NPSR1 | |
| SCHEMBL27123888 | 0.92 | MGLL (0.39) | MGLLTSHRHSD11B1CCR3NPSR1 | |
| SCHEMBL31697885 | 0.92 | MGLL (0.39) | MGLLTSHRHSD11B1CCR3NPSR1 | |
| SCHEMBL31677239 | 0.91 | DRD2 (0.45) | — | |
| SCHEMBL27146833 | 0.91 | MGLL (0.38) | MGLLTSHR | |
| SCHEMBL30966215 | 0.91 | MGLL (0.38) | MGLLTSHRHSD11B1CCR3 | |
| SCHEMBL29281606 | 0.90 | DDB1 (0.38) | MGLL | |
| SCHEMBL29201756 | 0.89 | KMT2A (0.37) | MGLLTSHRHSD11B1NPSR1 | |
| SCHEMBL29277059 | 0.89 | HSD11B1 (0.39) | MGLLTSHRHSD11B1CCR3NPSR1 | |
| SCHEMBL28891876 | 0.88 | NR3C1 (0.38) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |