Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475977 | 0.82 | FAAH (0.43) | FAAHMGLLSIGMAR1 | |
| SCHEMBL25364854 | 0.81 | FAAH (0.33) | FAAHMGLLSIGMAR1 | |
| SCHEMBL19988061 | 0.78 | ALDH1A1 (0.35) | SIGMAR1IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL30267357 | 0.74 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL30459684 | 0.74 | MEN1 (0.36) | FAAHMGLLALDH1A1 | |
| SCHEMBL25337571 | 0.74 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL23705972 | 0.73 | FAAH (0.32) | FAAHMGLLSIGMAR1 | |
| SCHEMBL30266977 | 0.72 | KDM5A (0.39) | — | |
| SCHEMBL30267087 | 0.71 | FAAH (0.33) | FAAHMGLLSIGMAR1 | |
| SCHEMBL29768147 | 0.71 | IRAK4 (0.32) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |