Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825704 | 0.79 | — | — | |
| SCHEMBL28459957 | 0.79 | CYP1A2 (0.33) | — | |
| SCHEMBL26618201 | 0.79 | IDH1 (0.32) | — | |
| SCHEMBL30267357 | 0.78 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1C5AR1PARP1 | |
| SCHEMBL30267191 | 0.78 | FAAH (0.32) | ALDH1A1L3MBTL1SIGMAR1IDO1 | |
| SCHEMBL27568268 | 0.76 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL26101147 | 0.76 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL138290 | 0.75 | HPGD (0.31) | C5AR1 | |
| SCHEMBL1359707 | 0.73 | ALDH1A1 (0.32) | ALDH1A1C5AR1MAPTSMN1; SMN2 | |
| SCHEMBL633502 | 0.72 | MPO (0.48) | ALDH1A1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878601-B1 | AGENT FOR TREATING OR CONTROLLING RECURRENCE OF ACUTE MYELOGENOUS LEUKEMIA | RIKEN (JP) | 2018-03-28 | — | — | EP | disclosed |