Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650981 | 1.00 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL29598381 | 0.88 | DPP4 (0.41) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL1167126 | 0.88 | DPP4 (0.41) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL523311 | 0.87 | GRIA1 (0.35) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL31152 | 0.87 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL31487599 | 0.87 | LOXL2 (0.35) | GRIA1GRIA2GRIA3GRIA4PDE4A | |
| SCHEMBL25354840 | 0.81 | TP53 (0.32) | GPR84 | |
| SCHEMBL3824032 | 0.81 | POLB (0.33) | GPR84APEX1 | |
| SCHEMBL2209800 | 0.81 | DPP4 (0.33) | DPP4MEN1GAPDHTHRBAPEX1 | |
| SCHEMBL3872724 | 0.81 | TP53 (0.40) | GRIA1GRIA2GRIA3GRIA4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166085-B | Indane derivatives for the treatment of bacterial infections | 安塔比奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-110914238-B | Compounds as antibiotics | 安塔比奥公司 | 2023-06-20 | — | — | CN | disclosed |
| EP-4125883-A1 | COMBINATION THERAPY | Antabio SAS (FR) | 2023-02-08 | — | — | EP | disclosed |