Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.41 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167126 | 1.00 | DPP4 (0.41) | DPP4USP28HDAC1HDAC8MMP2 | |
| SCHEMBL523311 | 0.94 | GRIA1 (0.35) | DPP4USP28KDM4EALDH1A1HPGD | |
| SCHEMBL30267640 | 0.88 | GRIA1 (0.40) | DPP4KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL650981 | 0.88 | GRIA1 (0.40) | DPP4KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL5398118 | 0.81 | CA3 (0.37) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL26291432 | 0.81 | — | — | |
| SCHEMBL14989586 | 0.79 | SHBG (0.38) | DPP4HDAC1KDM4EALDH1A1HPGD | |
| SCHEMBL856379 | 0.79 | KDM1A (0.39) | USP28MAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL3062649 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL2034552 | 0.79 | PTPN1 (0.33) | USP28CA2MAPK1MAP2K4MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178129-B | Preparation method of 2,4, 5-trifluoro-benzoic acid | 浙江永太科技股份有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-116178129-A | Preparation method of 2,4, 5-trifluoro-benzoic acid | 浙江永太科技股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115677477-B | Preparation method of 2,4, 5-trifluoro-phenylacetic acid and intermediate thereof | 上海康鹏科技股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-115677477-A | Preparation method of 2,4, 5-trifluoro-phenylacetic acid and intermediate thereof | 上海康鹏科技股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114773147-A | Preparation method of 2,4, 5-trifluorobenzyl bromide | 浙江永太科技股份有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-112341546-B | Preparation method of fluorinated biomass membrane material | 北京化工大学 | 2022-07-05 | — | — | CN | claimed |
| CN-116178129-B | Preparation method of 2,4, 5-trifluoro-benzoic acid | 浙江永太科技股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-116178129-B | Preparation method of 2,4, 5-trifluoro-benzoic acid | 浙江永太科技股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024220917-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-116082563-B | (Meth) acrylate compound, optical resin additive, optical element, and optical device | 株式会社 尼康 | 2024-09-20 | — | — | CN | disclosed |
| CN-118359760-A | Optical resin, optical element, and optical device | 株式会社 尼康 | 2024-07-19 | — | — | CN | disclosed |
| US-11999746-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-06-04 | — | — | US | disclosed |
| CN-114605223-B | Method for preparing 2,4, 5-trifluoro-benzyl bromide by using 2,4, 5-trifluoro-benzyl chloride | 浙江永太科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-111253415-B | Norcantharidin carboxylic acid trifluoro benzyl ester and synthetic method and application thereof | 遵义医科大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114853560-A | Preparation method of 2,4, 5-trifluorobenzyl bromide and 2,4, 5-trifluorobenzoic acid | 湖南复瑞生物医药技术有限责任公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114773147-A | Preparation method of 2,4, 5-trifluorobenzyl bromide | 浙江永太科技股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114773147-A | Preparation method of 2,4, 5-trifluorobenzyl bromide | 浙江永太科技股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112341546-B | Preparation method of fluorinated biomass membrane material | 北京化工大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-114605223-A | Method for preparing 2,4, 5-trifluorobenzyl bromide by using 2,4, 5-trifluorobenzyl chloride | 浙江永太科技股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114591141-A | Preparation method of 2,4, 5-trifluorobenzyl bromide | 浙江永太科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999746-B2 | Compounds | PLAAT2, PLA2G12A, PLA2G1B | DPP4 357/4885USP28 2787/4885HDAC1 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.