Sugi Predict

Sugi Predict / Compounds / SCHEMBL650981

SCHEMBL650981

SCHEMBL650981

OCc1cc(F)c(F)cc1CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIA1 P42261 1/20 0.40
▸ GRIA2 P42262 1/20 0.40
▸ GRIA3 P42263 1/20 0.40
▸ GRIA4 P48058 1/20 0.40
▸ PDE4A P27815 1/20 0.39
▸ PDE4B Q07343 1/20 0.39
▸ PDE4C Q08493 1/20 0.39
▸ PDE4D Q08499 1/20 0.39
▸ DPP4 P27487 3/20 0.34
▸ KDM4E B2RXH2 1/20 0.32
▸ CASP6 P55212 1/20 0.32
▸ GPR84 Q9NQS5 1/20 0.31
▸ SHBG P04278 1/20 0.31
▸ CES2 O00748 1/20 0.31
▸ CES1 P23141 1/20 0.31
▸ APOBEC3G Q9HC16 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ GAPDH P04406 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30267640 1.00 GRIA1 (0.40) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL29598381 0.88 DPP4 (0.41) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL1167126 0.88 DPP4 (0.41) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL523311 0.87 GRIA1 (0.35) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL31152 0.87 GRIA1 (0.33) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL31487599 0.87 LOXL2 (0.35) GRIA1GRIA2GRIA3GRIA4PDE4A
SCHEMBL25354840 0.81 TP53 (0.32) GPR84
SCHEMBL3824032 0.81 POLB (0.33) GPR84APEX1
SCHEMBL2209800 0.81 DPP4 (0.33) DPP4MEN1GAPDHTHRBAPEX1
SCHEMBL3872724 0.81 TP53 (0.40) GRIA1GRIA2GRIA3GRIA4PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286411-B2 Indane derivatives for use in the treatment of bacterial infection ANTABIO SAS (FR) 2025-04-29 — — US disclosed
US-12247013-B2 Indane derivatives for use in the treatment of bacterial infection ANTABIO SAS (FR) 2025-03-11 — — US disclosed
CN-113166084-B Indane derivatives for the treatment of bacterial infections 安塔比奥公司 2024-06-04 — — CN disclosed
CN-113166085-B Indane derivatives for the treatment of bacterial infections 安塔比奥公司 2024-04-09 — — CN disclosed
US-20240016941-A1 COMBINATION THERAPY ANTABIO SAS (FR) 2024-01-18 — — US disclosed
US-20240016941-A1 COMBINATION THERAPY ANTABIO SAS (FR) 2024-01-18 — — US disclosed
US-20240016941-A1 COMBINATION THERAPY ANTABIO SAS (FR) 2024-01-18 — — US disclosed
EP-3601224-B1 CHEMICAL COMPOUNDS AS ANTIBIOTICS ANTABIO SAS (FR) 2023-07-05 — — EP disclosed
EP-4125883-A1 COMBINATION THERAPY Antabio SAS (FR) 2023-02-08 — — EP disclosed
US-20220112169-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION ANTABIO SAS (FR) 2022-04-14 — — US disclosed
US-20070102696-A1 Organic semiconducting layers FLEXENABLE TECHNOLOGY LIMITED (GB) 2007-05-10 — — US disclosed
US-20070102696-A1 Organic semiconducting layers FLEXENABLE TECHNOLOGY LIMITED (GB) 2007-05-10 — — US disclosed
US-20070102696-A1 Organic semiconducting layers FLEXENABLE TECHNOLOGY LIMITED (GB) 2007-05-10 — — US disclosed
EP-1783781-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS Merck Patent GmbH (DE) 2007-05-09 — — EP disclosed
EP-1783781-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS Merck Patent GmbH (DE) 2007-05-09 — — EP disclosed
US-20060223830-A1 Indanyl-piperazine compounds LES LABORATOIRES SERVIER (FR) 2006-10-05 — — US disclosed
WO-2006103342-A2 INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2006-10-05 — — WO disclosed
EP-1707564-A2 Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them Les Laboratoires Servier (FR) 2006-10-04 — — EP disclosed
EP-1687830-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS Merck Patent GmbH (DE) 2006-08-09 — — EP disclosed
WO-2005055248-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS MERCK PATENT GMBH (DE) 2005-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112169-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION ARG1, ELANE, INSR GRIA1 3054/4885GRIA2 3885/4885GRIA3 4148/4885
US-20060223830-A1 Indanyl-piperazine compounds HTR4, NR4A1, NR4A3 GRIA1 404/4885GRIA2 384/4885GRIA3 204/4885
US-12286411-B2 Indane derivatives for use in the treatment of bacterial infection ELANE, ARG1, INSRR GRIA1 3080/4885GRIA2 3968/4885GRIA3 4273/4885
US-20240016941-A1 COMBINATION THERAPY CFTR, ABCB11, SLC26A4 GRIA1 1000/4885GRIA2 1634/4885GRIA3 2152/4885
US-20070102696-A1 Organic semiconducting layers SSB, RCOR3, CNKSR1 GRIA1 3292/4885GRIA2 2864/4885GRIA3 1612/4885
US-12247013-B2 Indane derivatives for use in the treatment of bacterial infection ELANE, ARG1, INSRR GRIA1 3080/4885GRIA2 3968/4885GRIA3 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.