Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213120 | 1.00 | PRMT6 (0.43) | PRMT6CARM1PRMT8KDM1AHDAC6 | |
| SCHEMBL30270456 | 0.89 | CARM1 (0.43) | PRMT6CARM1KDM1AHDAC6SLC6A2 | |
| SCHEMBL26213112 | 0.89 | CARM1 (0.43) | PRMT6CARM1KDM1AHDAC6SLC6A2 | |
| SCHEMBL26213116 | 0.88 | KDM1A (0.43) | PRMT6CARM1KDM1AHDAC6SLC6A2 | |
| SCHEMBL26213169 | 0.82 | CYP3A4 (0.43) | PRMT6CARM1KDM1AHDAC6L3MBTL1 | |
| SCHEMBL26213111 | 0.81 | L3MBTL1 (0.42) | PRMT6CARM1KDM1AHDAC6SLC6A2 | |
| SCHEMBL26213109 | 0.79 | KDM1A (0.41) | PRMT6CARM1KDM1AHDAC6SLC6A2 | |
| SCHEMBL26213680 | 0.77 | PRMT6 (0.50) | PRMT6CARM1PRMT8SLC6A2SLC6A4 | |
| SCHEMBL26213056 | 0.76 | KDM1A (0.53) | KDM1AHTR1AHTR7SIGMAR1 | |
| SCHEMBL30270494 | 0.75 | HTR7 (0.54) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843271-B | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |