Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728575 | 0.84 | KDM5A (0.42) | KDM5ARORCHTTATMGPR119 | |
| SCHEMBL30318388 | 0.83 | KDM5A (0.44) | KDM5AFPR2RORCUSP30NR1H2 | |
| SCHEMBL21791736 | 0.82 | ALDH1A1 (0.41) | KDM5AFPR2RORCUSP30NR1H2 | |
| SCHEMBL31228739 | 0.77 | KDM5A (0.45) | KDM5AFPR2HTTATMGPR119 | |
| SCHEMBL31228630 | 0.75 | KDM5A (0.43) | KDM5AFPR2HTTATMGPR119 | |
| SCHEMBL31237017 | 0.75 | PIK3CA (0.43) | KDM5AHTTGPR119 | |
| SCHEMBL21997425 | 0.74 | CTSD (0.43) | HTTGPR119 | |
| SCHEMBL28457723 | 0.74 | USP30 (0.44) | KDM5AFPR2RORCUSP30KCNK3 | |
| SCHEMBL3598372 | 0.74 | KDM5A (0.43) | KDM5AFPR2RORCUSP30NR1H2 | |
| SCHEMBL31056160 | 0.74 | FPR2 (0.42) | FPR2RORCUSP30NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387964-A1 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023027948-A1 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |