Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397009 | 0.93 | TLR9 (0.35) | TLR9TLR7PRMT5GPR119MEN1 | |
| SCHEMBL23540926 | 0.89 | NAMPT (0.41) | PRMT5GPR119GRM5 | |
| SCHEMBL31323560 | 0.86 | PRMT5 (0.37) | TLR9TLR7PRMT5GPR119MEN1 | |
| SCHEMBL31397238 | 0.83 | TLR9 (0.38) | TLR9TLR7PRMT5GPR119MEN1 | |
| SCHEMBL23541226 | 0.83 | GHSR (0.35) | TLR9TLR7PRMT5GPR119GRM5 | |
| SCHEMBL23541225 | 0.83 | GHSR (0.35) | TLR9TLR7PRMT5GPR119GRM5 | |
| SCHEMBL31397309 | 0.83 | GHSR (0.35) | TLR9TLR7PRMT5GPR119GRM5 | |
| SCHEMBL23540770 | 0.83 | TLR9 (0.34) | TLR9TLR7PRMT5GPR119MEN1 | |
| SCHEMBL24819532 | 0.83 | GHSR (0.35) | TLR9TLR7PRMT5GPR119GRM5 | |
| SCHEMBL23541288 | 0.83 | GPR119 (0.47) | TLR9TLR7GPR119ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |