Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431573 | 0.84 | MEN1 (0.57) | POLBKDM4ETSHRALDH1A1LMNA | |
| SCHEMBL4428749 | 0.81 | ALDH1A1 (0.60) | POLBKDM4ETSHRALDH1A1LMNA | |
| SCHEMBL31692132 | 0.79 | TSHR (0.47) | POLBKDM4ENR3C1TSHRALDH1A1 | |
| SCHEMBL30273732 | 0.75 | POLB (0.41) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL4428794 | 0.74 | LMNA (0.53) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL12386396 | 0.72 | KDM4E (0.71) | POLBKDM4EALDH1A1LMNA | |
| SCHEMBL5325263 | 0.71 | CYP2C9 (0.49) | TSHRALDH1A1LMNAMAPT | |
| SCHEMBL30274022 | 0.70 | NR3C1 (0.41) | POLBKDM4ENR3C1TSHRALDH1A1 | |
| SCHEMBL7131786 | 0.70 | TSHR (0.62) | POLBTSHRALDH1A1LMNAMEN1 | |
| SCHEMBL28572837 | 0.70 | KMT2A (0.38) | POLBKDM4ETSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |