Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HEXA | P06865 | 1/20 | 0.47 |
| ▸ | HEXB | P07686 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26813895 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL26101354 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL30392446 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL30392640 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL3892107 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL23720311 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL19541802 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL5371487 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL230525 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAHPGDNPSR1RAB9A | |
| SCHEMBL30274320 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAHPGDNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| EP-3886904-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024220937-A2 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-10 | — | — | US | disclosed |
| CN-118382435-A | 12/15-Lipoxygenase inhibitors | 总医院公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-4384161-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | The General Hospital Corporation (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023019090-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, CSNK2A1, CSNK2A2 | SMN1; SMN2 1897/4885GAA 2767/4885HPGD 3257/4885 |
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | ALOX15, LOX, ALOX12 | SMN1; SMN2 729/4885GAA 647/4885HPGD 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.