Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL18260153 | 1.00 | POLB (0.42) | POLBTXNRD1LMNATDP1NFE2L2 | |
| Sulfuric Acid SCHEMBL18260154 | 1.00 | POLB (0.42) | POLBTXNRD1LMNATDP1NFE2L2 | |
| SCHEMBL28188442 | 0.94 | LMNA (0.47) | POLBTXNRD1LMNATDP1NFE2L2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8916452 | 0.88 | GAA (0.41) | POLBTXNRD1LMNATDP1NFE2L2 | |
| SCHEMBL15561907 | 0.87 | KDM4E (0.50) | POLBLMNATDP1TSHRATM | |
| SCHEMBL29531218 | 0.87 | — | — | |
| SCHEMBL65664 | 0.87 | — | — | |
| Formaldehyde SCHEMBL27574636 | 0.85 | KDM4E (0.44) | POLBTXNRD1LMNATDP1TSHR | |
| Formaldehyde SCHEMBL28791505 | 0.85 | KDM4E (0.44) | POLBTXNRD1LMNATDP1TSHR | |
| Hydrochloric Acid SCHEMBL7736230 | 0.85 | KDM4E (0.48) | POLBLMNATDP1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250041223-A1 | LIPOSOME LOADING | PLUMB PHARMACEUTICALS, INC. | 2025-02-06 | — | — | US | disclosed |
| US-12059499-B2 | Liposome loading | PLUMB PHARMACEUTICALS, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| EP-4212148-A1 | LIPOSOME LOADING | Plumb Pharmaceuticals, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| EP-3302435-B1 | LIPOSOME LOADING | PLUMB PHARMACEUTICALS INC (US) | 2023-03-08 | — | — | EP | disclosed |