Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 9/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24109559 | 1.00 | MAT2A (0.43) | MAT2AMAPK14BACE1PIK3CADCTPP1 | |
| SCHEMBL24109555 | 0.83 | MAT2A (0.57) | MAT2A | |
| SCHEMBL30277843 | 0.83 | MAT2A (0.57) | MAT2A | |
| SCHEMBL24109558 | 0.81 | MAT2A (0.45) | MAT2ADCTPP1MEN1MAPTKMT2A | |
| SCHEMBL24110104 | 0.69 | MAT2A (0.69) | MAT2A | |
| SCHEMBL29893575 | 0.69 | MAT2A (0.71) | MAT2A | |
| SCHEMBL24109554 | 0.69 | MAT2A (0.71) | MAT2A | |
| SCHEMBL30283089 | 0.69 | MAT2A (0.54) | MAT2A | |
| SCHEMBL24154771 | 0.69 | MAT2A (0.54) | MAT2A | |
| SCHEMBL24155083 | 0.68 | MAT2A (0.71) | MAT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165040-A1 | 2-AMINOQUINAZOLINONE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | Ideaya Biosciences, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |