Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735866 | 1.00 | MTNR1A (0.51) | MTNR1ANPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL6800337 | 0.88 | ALDH1A1 (0.49) | MTNR1AALDH1A1FFAR1MAPK1ALOX5 | |
| SCHEMBL15865435 | 0.88 | MTNR1A (0.52) | MTNR1ANPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL15865437 | 0.88 | MTNR1A (0.52) | MTNR1ANPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL30640313 | 0.88 | ALDH1A1 (0.49) | MTNR1AALDH1A1FFAR1MAPK1ALOX5 | |
| SCHEMBL30640308 | 0.88 | ALDH1A1 (0.49) | MTNR1AALDH1A1FFAR1MAPK1ALOX5 | |
| SCHEMBL6794906 | 0.88 | MTNR1A (0.49) | MTNR1ANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16070931 | 0.85 | HPGD (0.48) | MTNR1ANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16061961 | 0.84 | DRD2 (0.48) | MTNR1ANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5992714 | 0.83 | KDM4E (0.48) | MTNR1ANPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |