Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735705 | 1.00 | CA12 (0.46) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28206684 | 0.81 | CA12 (0.49) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19500875 | 0.80 | CA12 (0.47) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18114479 | 0.78 | RAB9A (0.49) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23800712 | 0.77 | NPC1 (0.48) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30278220 | 0.75 | KDM4E (0.61) | SMN1; SMN2MAPTHSD17B10TSHRALOX15 | |
| SCHEMBL24735730 | 0.75 | KDM4E (0.61) | SMN1; SMN2MAPTHSD17B10TSHRALOX15 | |
| SCHEMBL15865437 | 0.74 | MTNR1A (0.52) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15865435 | 0.74 | MTNR1A (0.52) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16372412 | 0.74 | MTNR1A (0.46) | NPC1RAB9ASMN1; SMN2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |