Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978802 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2PKMALDH1A1MAPTEZH2 | |
| SCHEMBL23978794 | 0.88 | — | — | |
| SCHEMBL30279399 | 0.82 | GRM5 (0.36) | SMN1; SMN2PKMALDH1A1MAPTEZH2 | |
| SCHEMBL23978787 | 0.82 | GRM5 (0.36) | SMN1; SMN2PKMALDH1A1MAPTEZH2 | |
| SCHEMBL23978723 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMALDH1A1MAPTLMNA | |
| SCHEMBL10129825 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2PKMALDH1A1MAPTLMNA | |
| SCHEMBL30279422 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2PKMALDH1A1MAPTLMNA | |
| SCHEMBL30279426 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMALDH1A1MAPTLMNA | |
| SCHEMBL30279429 | 0.76 | EZH2 (0.32) | EZH2 | |
| SCHEMBL23978800 | 0.76 | MAPK1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |