Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DHPS | P49366 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978798 | 1.00 | P2RX7 (0.48) | P2RX7ALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL23978727 | 0.92 | DHPS (0.48) | ALDH1A1MAPTCYP2C9CYP2C19DHPS | |
| SCHEMBL30279428 | 0.92 | DHPS (0.48) | ALDH1A1MAPTCYP2C9CYP2C19DHPS | |
| SCHEMBL30279391 | 0.89 | SMN1; SMN2 (0.46) | ALDH1A1DHPSSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23978742 | 0.89 | SMN1; SMN2 (0.46) | ALDH1A1DHPSSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10129824 | 0.89 | SMN1; SMN2 (0.45) | P2RX7ALDH1A1HPGDDHPSSMN1; SMN2 | |
| SCHEMBL30279449 | 0.89 | SMN1; SMN2 (0.45) | P2RX7ALDH1A1HPGDDHPSSMN1; SMN2 | |
| SCHEMBL23978872 | 0.89 | P2RX7 (0.46) | P2RX7ALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL23978808 | 0.88 | SMN1; SMN2 (0.47) | P2RX7ALDH1A1HPGDMAPTCYP2C9 | |
| SCHEMBL30279364 | 0.88 | SMN1; SMN2 (0.47) | P2RX7ALDH1A1HPGDMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |