SCHEMBL30280286

SCHEMBL30280286

CON(C)C(=O)[C@@H](C)OC(C)(C)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.34
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29224151 0.73 FAAH (0.33) FAAH
SCHEMBL30280001 0.73 FAAH (0.34) MLYCDFAAH
SCHEMBL30280216 0.73 FAAH (0.34) MLYCDFAAH
SCHEMBL30322880 0.72 TP53 (0.32)
SCHEMBL29183039 0.72 FAAH (0.41) FAAH
SCHEMBL30281294 0.71 LMNA (0.31)
SCHEMBL18099957 0.69 FAAH (0.39) FAAH
SCHEMBL30001908 0.69 FAAH (0.39) FAAH
SCHEMBL14406309 0.68 FAAH (0.33) FAAH
SCHEMBL16516677 0.68 FAAH (0.33) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4408837-A1 BENZIMIDAZOLE AND AZABENZIMIDAZOLE IL-17 INHIBITOR COMPOUNDS JANSSEN Pharmaceutica NV (BE) 2024-08-07 EP disclosed
EP-4408530-A1 BENZIMIDAZOLES AS MODULATORS OF IL-17 Janssen Pharmaceutica NV (BE) 2024-08-07 EP disclosed
WO-2023049885-A1 BENZIMIDAZOLE AND AZABENZIMIDAZOLE IL-17 INHIBITOR COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2023-03-30 WO disclosed
WO-2023049888-A1 BENZIMIDAZOLES AS MODULATORS OF IL-17 JANSSEN PHARMACEUTICA NV (BE) 2023-03-30 WO disclosed