Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280863 | 0.85 | DRD2 (0.32) | PDK2PDK4ALDH1A1KDM4EOPRK1 | |
| SCHEMBL12488339 | 0.79 | FASN (0.38) | PDK2PDK4SLC6A3 | |
| SCHEMBL30281000 | 0.78 | HSD17B10 (0.39) | PDK2PDK4ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL30280829 | 0.77 | ALDH1A1 (0.34) | PDK2PDK4ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL30281011 | 0.76 | OPRK1 (0.39) | PDK2PDK4ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL12488689 | 0.75 | MEN1 (0.33) | PDK2PDK4ALDH1A1KDM4EOPRK1 | |
| SCHEMBL12488738 | 0.73 | PDK2 (0.38) | PDK2PDK4ALDH1A1KDM4ELMNA | |
| SCHEMBL30280860 | 0.73 | FASN (0.39) | PDK2PDK4ALDH1A1KDM4EHSP90AA1 | |
| SCHEMBL12489060 | 0.73 | PDK2 (0.38) | PDK2PDK4ALDH1A1KDM4ELMNA | |
| SCHEMBL30280814 | 0.72 | FASN (0.40) | PDK2PDK4OPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |