Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280880 | 0.95 | PTGER4 (0.41) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30280992 | 0.83 | PTGER4 (0.43) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL30280908 | 0.80 | PTGER4 (0.41) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30281055 | 0.79 | ALDH1A1 (0.40) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30280727 | 0.79 | PTGER4 (0.41) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30280774 | 0.78 | KDM4E (0.37) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30281031 | 0.78 | PTGER4 (0.38) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30410057 | 0.76 | PDK2 (0.52) | PTGER4PDK2PDK4ALDH1A1KDM4E | |
| SCHEMBL30280725 | 0.76 | PTGER4 (0.44) | PTGER4ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL30280983 | 0.75 | PTGER4 (0.41) | PTGER4PDK2PDK4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |