Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23990298 | 0.83 | NOTUM (0.37) | KDM4C | |
| SCHEMBL30281218 | 0.82 | KMT2A (0.34) | DRD2DRD3 | |
| SCHEMBL14825920 | 0.76 | L3MBTL1 (0.46) | KDM4C | |
| SCHEMBL23990475 | 0.75 | KDM4C (0.33) | KDM4CATM | |
| SCHEMBL23989768 | 0.73 | CNR1 (0.32) | — | |
| SCHEMBL23989879 | 0.73 | L3MBTL1 (0.31) | — | |
| SCHEMBL23990554 | 0.71 | ATM (0.35) | KDM4CATM | |
| SCHEMBL30209669 | 0.69 | SIRT2 (0.36) | — | |
| SCHEMBL400637 | 0.69 | LMNA (0.35) | — | |
| SCHEMBL23989818 | 0.69 | ACACB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |