Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745169 | 0.86 | ATM (0.33) | ATM | |
| SCHEMBL30281208 | 0.84 | PIK3CA (0.41) | ATMPIK3CAADRA1APIK3CDPIK3CG | |
| SCHEMBL23990475 | 0.83 | KDM4C (0.33) | ATML3MBTL1KDM4C | |
| SCHEMBL23990535 | 0.80 | NPC1 (0.33) | PIK3CAADRA1APIK3CDPIK3CG | |
| SCHEMBL23989879 | 0.77 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL23989768 | 0.74 | CNR1 (0.32) | L3MBTL1 | |
| SCHEMBL14825920 | 0.73 | L3MBTL1 (0.46) | L3MBTL1KDM4C | |
| SCHEMBL28976350 | 0.72 | ATM (0.31) | ATM | |
| SCHEMBL30281171 | 0.71 | KDM4C (0.34) | ATMKDM4C | |
| SCHEMBL30281146 | 0.71 | PIK3CA (0.33) | ATMPIK3CAPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222404-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN BIOTECH, INC. (US) | 2021-11-04 | — | — | WO | disclosed |