SCHEMBL30282930

SCHEMBL30282930

O=C1CN2CCNCC2C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 12/20 0.42
HTR2A P28223 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CRBN Q96SW2 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
MEN1 O00255 1/20 0.35
APEX1 P27695 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HTR2B P41595 1/20 0.35
KDM4E B2RXH2 1/20 0.34
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337063 0.75 ALDH1A1 (0.60) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
SCHEMBL25043852 0.75 ALDH1A1 (0.60) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL26110115 0.73 ALDH1A1 (0.58) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL29792081 0.73 ALDH1A1 (0.58) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
SCHEMBL27123348 0.73 ALDH1A1 (0.53) ALDH1A1CYP1A2CRBNMEN1APEX1
SCHEMBL5579426 0.73 ALDH1A1 (0.53) ALDH1A1CYP1A2CRBNMEN1APEX1
SCHEMBL2966923 0.73 ALDH1A1 (0.44) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
SCHEMBL8769343 0.73 KMT2A (0.56) HTR2CALDH1A1CYP1A2CRBNTAAR1
Hydrochloric Acid SCHEMBL26110112 0.73 ALDH1A1 (0.58) HTR2CHTR2AALDH1A1CYP1A2CYP3A4
SCHEMBL2161211 0.71 HTR2C (0.57) HTR2CHTR2AALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703765-A Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof 上海赛默罗生物科技有限公司 2023-02-17 CN disclosed