Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382788 | 0.90 | POLB (0.53) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL18712984 | 0.87 | SLC6A1 (0.47) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL10265288 | 0.85 | POLB (0.53) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL20159607 | 0.85 | L3MBTL1 (0.51) | POLBTSHRL3MBTL1CYP3A4RAB9A | |
| SCHEMBL18712990 | 0.84 | POLB (0.65) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL3329374 | 0.82 | POLB (0.59) | POLBL3MBTL1KDM5AALDH1A1MAPK1 | |
| SCHEMBL25043979 | 0.81 | TSHR (0.45) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL14820327 | 0.81 | POLB (0.41) | POLBTSHRL3MBTL1KDM5ACYP3A4 | |
| SCHEMBL17625632 | 0.81 | L3MBTL1 (0.57) | POLBTSHRL3MBTL1CYP3A4RAB9A | |
| SCHEMBL13783325 | 0.81 | L3MBTL1 (0.61) | TSHRL3MBTL1CYP3A4RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |