Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 13/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27242729 | 1.00 | GABRA5 (0.41) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL30283010 | 0.88 | GRIN1 (0.33) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL27242745 | 0.88 | GRIN1 (0.33) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL2688352 | 0.86 | GABRA5 (0.54) | GABRA5GABRG2GABRB3KCNH2PTGS2 | |
| SCHEMBL30282901 | 0.86 | GABRA5 (0.54) | GABRA5GABRG2GABRB3KCNH2PTGS2 | |
| SCHEMBL25045281 | 0.85 | GABRA5 (0.41) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL29036226 | 0.78 | GABRG2 (0.38) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL25045396 | 0.76 | GABRA5 (0.44) | GABRA5GABRG2GABRB3KCNH2PTGS2 | |
| SCHEMBL25044752 | 0.76 | GABRA5 (0.44) | GABRA5GABRG2GABRB3KCNH2RXRA | |
| SCHEMBL25045411 | 0.75 | NOTUM (0.37) | GABRA5GABRG2GABRB3KCNH2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |