Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781984 | 0.89 | OPRM1 (0.43) | OPRM1OPRD1KMT2ADPP4FAP | |
| SCHEMBL30297051 | 0.88 | APLNR (0.47) | OPRM1OPRD1APLNR | |
| SCHEMBL30431697 | 0.86 | F2 (0.45) | F2NTMT1MEN1TP53CYP1A2 | |
| SCHEMBL29423417 | 0.86 | APLNR (0.45) | OPRM1NTMT1OPRD1APLNR | |
| SCHEMBL29752677 | 0.86 | OPRM1 (0.60) | OPRM1F2DPP4FAPDPP8 | |
| SCHEMBL31661806 | 0.85 | APLNR (0.47) | OPRM1F2NTMT1APLNR | |
| SCHEMBL10396256 | 0.84 | MEN1 (0.49) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29666108 | 0.84 | APLNR (0.47) | OPRD1MEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL29569081 | 0.83 | F2 (0.47) | OPRM1F2NTMT1OPRD1APLNR | |
| SCHEMBL30918789 | 0.83 | OPRM1 (0.46) | OPRM1F2NTMT1OPRD1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476732-B | Trispecific and/or trivalent binding proteins | 赛诺菲 | 2024-03-22 | — | — | CN | disclosed |
| CN-117069855-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-11-17 | — | — | CN | disclosed |
| CN-116789841-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-09-22 | — | — | CN | disclosed |
| CN-116675776-A | Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection | 赛诺菲 | 2023-09-01 | — | — | CN | disclosed |
| CN-109311966-B | Trispecific and/or trivalent binding proteins for use in the prevention or treatment of HIV infection | 赛诺菲 | 2023-03-10 | — | — | CN | disclosed |