Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.36 |
| ▸ | SDHB | P21912 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513124 | 1.00 | POLB (0.40) | POLBKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL19512883 | 0.89 | TSPO (0.43) | KDM4EALDH1A1ALOX15HSD17B10GRM5 | |
| SCHEMBL19512656 | 0.89 | LTB4R2 (0.38) | KDM4EALDH1A1ALOX15HSD17B10CNR1 | |
| SCHEMBL19512884 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1ALOX15HSD17B10CNR1 | |
| SCHEMBL20936928 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1ALOX15HSD17B10GRM5 | |
| SCHEMBL19512686 | 0.84 | LTB4R2 (0.39) | POLBKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL20936941 | 0.83 | LMNA (0.42) | KDM4EALDH1A1ALOX15HSD17B10GRM5 | |
| SCHEMBL28998282 | 0.83 | SYK (0.43) | POLBKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL19512687 | 0.76 | LTB4R2 (0.37) | POLBKDM4ECNR1CNR2GRM5 | |
| SCHEMBL19474957 | 0.76 | POLB (0.48) | POLBKDM4EALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |