Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19512884 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL19512883 | 0.87 | TSPO (0.43) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL20936941 | 0.87 | LMNA (0.42) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL19513124 | 0.84 | POLB (0.40) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL30285223 | 0.84 | POLB (0.40) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL19512656 | 0.83 | LTB4R2 (0.38) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL19512686 | 0.81 | LTB4R2 (0.39) | KDM4EALDH1A1ALOX15HSD17B10LMNA | |
| SCHEMBL19512887 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1ALOX15HSD17B10SLC6A3 | |
| SCHEMBL20936927 | 0.78 | SLC6A3 (0.49) | KDM4EALDH1A1HSD17B10SLC6A3SLC6A4 | |
| SCHEMBL30285019 | 0.75 | KMT2A (0.46) | KDM4EALDH1A1ALOX15HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696635-B2 | Versatile ligand for palladium-catalyzed meta-C—H functionalizations of aromatic substrates | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190119212-A1 | A VERSATILE LIGAND FOR PALLADIUM-CATALYZED META-C-H FUNCTIONALIZATIONS | THE SCRIPPS RESEARCH INSTITUTE | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119212-A1 | A VERSATILE LIGAND FOR PALLADIUM-CATALYZED META-C-H FUNCTIONALIZATIONS | AHR, PAH, DOHH | KDM4E 3516/4885ALDH1A1 208/4885ALOX15 2078/4885 |
| US-10696635-B2 | Versatile ligand for palladium-catalyzed meta-C—H functionalizations of aromatic substrates | PAH, AHR, DDC | KDM4E 3453/4885ALDH1A1 121/4885ALOX15 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.