Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.33 |
| ▸ | SIK1 | P57059 | 1/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333743 | 1.00 | MAPT (0.50) | MAPTNPC1RAB9AKMT2AKMO | |
| SCHEMBL21351071 | 0.72 | NPC1 (0.44) | MAPTNPC1RAB9AKMT2AKMO | |
| SCHEMBL5863449 | 0.72 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1 | |
| SCHEMBL38656212 | 0.71 | NPC1 (0.43) | MAPTNPC1RAB9AKMT2AKMO | |
| SCHEMBL9146392 | 0.69 | PKM (0.53) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL14965798 | 0.69 | BRD4 (0.43) | NPC1RAB9ATDP1ALDH1A1MITF | |
| SCHEMBL6244218 | 0.68 | FGFR1 (0.44) | NPC1RAB9AKMT2AKMOMEN1 | |
| SCHEMBL5864145 | 0.68 | ALDH1A1 (0.46) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL409341 | 0.67 | MAPT (1.00) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL411024 | 0.67 | MAPT (1.00) | MAPTKMT2ASMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825656-B | Inhibitors of protein arginine methyltransferase 5 (PRMT 5), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2023-03-31 | — | — | CN | disclosed |