Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26186449 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL30285888 | 0.93 | ANO1 (0.48) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL26186445 | 0.93 | ANO1 (0.48) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL30285757 | 0.92 | ANO1 (0.47) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL24173312 | 0.92 | ANO1 (0.47) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL30285782 | 0.91 | ANO1 (0.46) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL24173311 | 0.91 | ANO1 (0.46) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL30285722 | 0.91 | ANO1 (0.46) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL26186458 | 0.91 | ANO1 (0.46) | ALDH1A1ANO1P2RX4SMN1; SMN2NPC1 | |
| SCHEMBL30285528 | 0.87 | KCNJ5 (0.50) | ALDH1A1ANO1P2RX4SMN1; SMN2KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-17 | — | — | US | disclosed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | P2RX2, P2RX5, P2RX3 | ALDH1A1 882/4885ANO1 964/4885P2RX4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.