Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26186447 | 1.00 | ROCK2 (0.44) | ROCK2P2RX7TP53KCNJ5KCNJ3 | |
| SCHEMBL30285728 | 0.94 | ROCK2 (0.48) | ROCK2P2RX7ALDH1A1ACKR3RECQL | |
| SCHEMBL26186448 | 0.94 | ROCK2 (0.48) | ROCK2P2RX7ALDH1A1ACKR3RECQL | |
| SCHEMBL26186457 | 0.93 | SMN1; SMN2 (0.46) | ROCK2P2RX7TP53KCNJ5KCNJ3 | |
| SCHEMBL30285736 | 0.93 | SMN1; SMN2 (0.46) | ROCK2P2RX7TP53KCNJ5KCNJ3 | |
| SCHEMBL30285795 | 0.90 | ROCK2 (0.45) | ROCK2P2RX7ALDH1A1SMN1; SMN2ACKR3 | |
| SCHEMBL26186464 | 0.90 | ROCK2 (0.45) | ROCK2P2RX7ALDH1A1SMN1; SMN2ACKR3 | |
| SCHEMBL30285528 | 0.88 | KCNJ5 (0.50) | ROCK2KCNJ5KCNJ3ALDH1A1SMN1; SMN2 | |
| SCHEMBL26186450 | 0.88 | KCNJ5 (0.50) | ROCK2KCNJ5KCNJ3ALDH1A1SMN1; SMN2 | |
| SCHEMBL30285692 | 0.88 | KCNJ5 (0.56) | ROCK2KCNJ5KCNJ3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-17 | — | — | US | disclosed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257351-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | P2RX2, P2RX5, P2RX3 | ROCK2 4776/4885P2RX7 6/4885TP53 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.