Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.47 |
| ▸ | THRB | P10828 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483303 | 0.91 | THRB (0.52) | THRATHRB | |
| SCHEMBL24132132 | 0.91 | THRB (0.52) | THRATHRB | |
| SCHEMBL30483270 | 0.89 | THRA (0.45) | THRATHRBHPGDMEN1KMT2A | |
| SCHEMBL24132129 | 0.89 | THRA (0.45) | THRATHRBHPGDMEN1KMT2A | |
| SCHEMBL25949916 | 0.87 | THRB (0.41) | THRATHRBSMN1; SMN2 | |
| SCHEMBL30285992 | 0.81 | THRB (0.56) | THRATHRBGAAHTTKDM4E | |
| SCHEMBL24132137 | 0.81 | THRB (0.56) | THRATHRBGAAHTTKDM4E | |
| SCHEMBL24132131 | 0.80 | THRB (0.48) | THRATHRBALDH1A1GAAHTT | |
| SCHEMBL30483308 | 0.80 | THRB (0.48) | THRATHRBALDH1A1GAAHTT | |
| SCHEMBL24132696 | 0.80 | THRB (0.46) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916740-A | Thyromimetic agents | 速通医疗公司 | 2023-04-04 | — | — | CN | disclosed |