Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.56 |
| ▸ | THRA | P10827 | 17/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24132137 | 1.00 | THRB (0.56) | THRBTHRAKDM4ERGS12LMNA | |
| SCHEMBL24132131 | 0.88 | THRB (0.48) | THRBTHRAGAAMAPTHTT | |
| SCHEMBL30483308 | 0.88 | THRB (0.48) | THRBTHRAGAAMAPTHTT | |
| SCHEMBL24132122 | 0.88 | THRA (0.54) | THRBTHRAKDM4ERGS12LMNA | |
| SCHEMBL24132132 | 0.84 | THRB (0.52) | THRBTHRA | |
| SCHEMBL30483303 | 0.84 | THRB (0.52) | THRBTHRA | |
| SCHEMBL24132696 | 0.84 | THRB (0.46) | THRBTHRA | |
| SCHEMBL23003622 | 0.81 | THRB (0.66) | THRBTHRA | |
| SCHEMBL30285802 | 0.81 | THRA (0.47) | THRBTHRAKDM4EGAAHPGD | |
| SCHEMBL24133278 | 0.80 | THRB (0.52) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528761-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| CN-115916740-A | Thyromimetic agents | 速通医疗公司 | 2023-04-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528761-B2 | Thyromimetics | TSHR, THRB, TTR | THRB 2/4885THRA 5/4885KDM4E 4087/4885 |
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | THRB 3/4885THRA 6/4885KDM4E 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.