Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.57 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.57 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | PRKX | P51817 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005424 | 1.00 | KCNJ5 (0.57) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL26186441 | 0.85 | KCNJ5 (0.59) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL30285495 | 0.85 | KCNJ5 (0.59) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL26186446 | 0.84 | KCNJ5 (0.56) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL30285692 | 0.84 | KCNJ5 (0.56) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL30403682 | 0.80 | ROCK2 (0.48) | KCNJ5KCNJ3ANO1MEN1KMT2A | |
| SCHEMBL29029217 | 0.80 | ROCK2 (0.48) | KCNJ5KCNJ3ANO1MEN1KMT2A | |
| SCHEMBL30403470 | 0.80 | SMN1; SMN2 (0.49) | KCNJ5KCNJ3KCNJ6ANO1MEN1 | |
| SCHEMBL29029246 | 0.80 | SMN1; SMN2 (0.49) | KCNJ5KCNJ3KCNJ6ANO1MEN1 | |
| SCHEMBL30285634 | 0.77 | P2RX4 (0.54) | KCNJ5KCNJ3KCNJ6CLK2PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |