SCHEMBL30285960

SCHEMBL30285960

COC(=O)[C@@H](OC)Oc1ccccc1Oc1cc(-n2c(=O)c(C)c(C(F)(F)F)n(C)c2=O)c(F)cc1Br

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 14/20 0.33
BCAT1 P54687 2/20 0.33
JAK2 O60674 2/20 0.32
BTK Q06187 2/20 0.32
BCAT2 O15382 1/20 0.31
SCN8A Q9UQD0 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30285924 1.00 DHODH (0.33) DHODHBCAT1JAK2BTKBCAT2
SCHEMBL30285945 0.85 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL30232261 0.85 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL30286056 0.85 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL25095592 0.85 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL31075143 0.83 BCAT1 (0.34) DHODHBCAT1BCAT2
SCHEMBL30285734 0.80 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL30285996 0.80 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL25096305 0.80 BCAT1 (0.36) DHODHBCAT1BCAT2
SCHEMBL25095591 0.78 BCAT1 (0.36) DHODHBCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127169-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRICULTURAL SOLUTIONS US LLC 2025-04-24 US disclosed
EP-4396165-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRICULTURAL SOLUTIONS SEED US LLC (US) 2024-07-10 EP disclosed
US-20230157289-A1 HERBICIDAL PHENYLURACILS BASF SE (DE) 2023-05-25 US disclosed
WO-2023031161-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF Agricultural Solutions Seed US LLC (US) 2023-03-09 WO disclosed
WO-2023030935-A1 METHOD FOR CONTROLLING PPO-I RESISTANT WEEDS BASF SE (DE) 2023-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127169-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES PPOX, PNPO, PAOX DHODH 10/4885BCAT1 665/4885JAK2 2567/4885
US-20230157289-A1 HERBICIDAL PHENYLURACILS PFAS, DDT, DPYD DHODH 18/4885BCAT1 1409/4885JAK2 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.